Herpes simplex virus Research

Animations of steps of HSV Infection and Replication

Encapsidation and Nuclear Egress

The procapsid proteins (UL18, UL19 and UL38) assemble around scaffolding proteins (UL26 and UL26.5) that are then digested away. The empty capsid incorporates DNA by means of the action of cleavage/packaging proteins (see the DNA replication animation). The capsid migrates to the nuclear membrane and buds into the lumen between the inner and outer nuclear membrane. This enveloped virion then enters the cytoplasm through fusion with the outer nuclear membrane.

Illustration and Flash animations by
Karin Christensen
Scientific, Medical and Veterinary Illustration.
Imagecyte.com

The animations are available for download for classroom teaching.

Animations

Additional Graphics

Herpes simplex virus Research

Animations of steps of HSV Infection and Replication

Encapsidation and Nuclear Egress

Animations

Additional Graphics


The Homepage of Dr. Edward K. Wagner
Herpes Virus Animations HSV structure Receptor Binding RNA Transcription in Productive Infection Latent Infections DNA Replication Encapsidation and Release Exploring Herpesvirus Research with Dr. Ed Wagner Herpes Simplex Virus (HSV) The HSV Genome HSV Replication Use of DNA Microarrays to Analyze Gene Expression in HSV Infected Cells Analysis of Herpes Simplex Virus Promoters Structural Properties of Herpes Simplex Virus Promoters Latent Infections by HSV Animations Construction of a HSV-1 DNA Microarray for Global Analysis of Transcript Abundance Time-dependant Changes in HSV-1 Transcript Abundance During Productive Infection Additional Graphics The Genetic and Transcription Map of the HSV-1 Genome Table of Genetic Functions Encoded by HSV-1 Table of Oligonucleotide Probes Used to Generate the HSV-1 DNA Microarray Back to Dr. Wagner's Homepage email ewagner@uci.edu More Herpesvirus links		Herpes simplex virus Research Animations of steps of HSV Infection and Replication Encapsidation and Nuclear Egress The procapsid proteins (UL18, UL19 and UL38) assemble around scaffolding proteins (UL26 and UL26.5) that are then digested away. The empty capsid incorporates DNA by means of the action of cleavage/packaging proteins (see the DNA replication animation). The capsid migrates to the nuclear membrane and buds into the lumen between the inner and outer nuclear membrane. This enveloped virion then enters the cytoplasm through fusion with the outer nuclear membrane. Illustration and Flash animations by Karin Christensen Scientific, Medical and Veterinary Illustration. Imagecyte.com The animations are available for download for classroom teaching. Exploring Herpes Virus Research with Dr. Wagner Herpes Simplex Virus (HSV) The HSV Genome HSV Replication Use of DNA Microarrays to Analyze Gene Expression in HSV Infected Cells Analysis of Herpes Simplex Virus Promoters Structural Properties of Herpes Simplex Virus Promoters Latent Infections by HSV Animations Construction of a HSV-1 DNA Microarray for Global Analysis of Transcript Abundance Time-dependant Changes in HSV-1 Transcript Abundance During Productive Infection Additional Graphics The Genetic and Transcription Map of the HSV-1 Genome Table of Genetic Functions Encoded by HSV-1 Table of Oligonucleotide Probes Used to Generate the HSV-1 DNA Microarray Back to Dr. Wagner's Homepage