Listed in reverse-chronological order. Numbered in chronological order
* = These are "co-first author" papers
39. DT Ho, AJ Bardwell, S Grewal, C Iverson and L Bardwell (2006)
Interacting JNK-docking sites in MKK7 promote binding and activation of JNK mitogen-activated protein kinases.
Journal of Biological Chemistry 281:13169-79.
Abstract
38. S Grewal, DM Molina and L Bardwell (2006)
Mitogen-activated protein kinase (MAPK)-docking sites in MAPK kinases function as tethers that are crucial for MAPK regulation in vivo.
Cellular Signalling 18:123-134.
Abstract
37. DM Molina, S Grewal and L Bardwell (2005)
Characterization of an ERK-binding domain in MITF and differential inhibition of ERK2-mediated substrate phosphorylation.
Journal of Biological Chemistry 280:42051-60.
Abstract
36. NL Komarova, X Zou, Q Nie and L Bardwell (2005)
A theoretical framework for specificity in cell signaling.
Molecular Systems Biology doi:10.1038/msb4100031, E1-E5.
Online/pdf
35. LJ Flatauer, S Zadeh and L Bardwell (2005)
MAP Kinases With Distinct Requirements for Ste5 Scaffolding Influence Signaling Specificity in Yeast
Molecular and Cellular Biology 25:1793-1803. Abstract -- Get pdf
34. L Bardwell (2005)
A walk-through of the yeast mating pheromone response pathway
Peptides 26:339-350. Abstract -- PDF
33. PJ Cullen, W Sabbagh, M Irick, E Graham, E van Olden, C Neal, J Delrow, L Bardwell and GF Sprague, Jr. (2004)
Msb2 is a Signaling Mucin at the Head of the Yeast Filamentous Growth MAPK Pathway
Genes & Development 18:1695-708. Abstract
32. AB Kusari*, DM Molina*, W Sabbagh Jr., C Lau and L Bardwell (2004)
A conserved protein interaction network involving the yeast MAP kinases Fus3 and Kss1
Journal of Cell Biology 164: 267-277. Abstract -- Get pdf
31. AJ Bardwell, M Abdollahi and L Bardwell (2004)
Anthrax lethal factor-cleavage products of mitogen-activated protein kinase (MAPK) kinases exhibit reduced binding to their cognate MAPKs
Biochemical Journal 378:569-77. Abstract
30. DT Ho, AJ Bardwell, M Abdollahi and L Bardwell (2003)
A docking site in MKK4 mediates high-affinity binding to JNK MAP kinases and competes with similar docking sites in JNK substrates
Journal of Biological Chemistry 278:32662-72. Abstract
29. AJ Bardwell, M Abdollahi and L Bardwell (2003)
Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity
Biochemical Journal 370:1077-1085. Abstract
28. W Sabbagh Jr, LJ Flatauer, AJ Bardwell and L Bardwell (2001)
Specificity of MAPK signaling in yeast differentiation involves transient vs. sustained MAPK activation.
Molecular Cell 8:683-691. Abstract
27. AJ Bardwell, LJ Flatauer, K Matsukuma, J Thorner and L Bardwell (2001)
A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission.
Journal of Biological Chemistry 276:10374-10386. Abstract
26. Bardwell, L., Cook, J.G., Zhu-Shimoni, J.X., Voora, D., and Thorner, J. (1998) Differential regulation of transcription: Repression by unactivated MAP kinase Kss1 requires the Dig1 and Dig2 proteins.
Proceedings National Academy of Sciences USA 95:15400-15405. Abstract
25. Bardwell, L., Cook, J.G., Voora, D., Baggott, D.M., Martinez, A.R., and Thorner, J. (1998)
Repression of the yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK.
Genes & Development 12:2887-98. Abstract
24. Cook, J.G., Bardwell, L. *, and Thorner, J. (1997)
Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signaling pathway.
Nature 390:85-89. Abstract
23. Cook, J.G., Bardwell, L., Kron, S.J. and Thorner, J. (1996)
Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae.
Genes & Development 10:2831-2848. Abstract
22. Bardwell, L. and Thorner, J. (1996)
A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKs.
Trends in Biochemical Sciences 21:373-374.
21. Bardwell, L., Cook, J.G., Chang, E.C., Cairns, B.R. and Thorner, J. (1996)
Signaling in the yeast pheromone response pathway: specific and high-affinity interaction of the MAP kinases (Kss1 and Fus3) with the upstream MAP kinase kinase (Ste7).
Molecular and Cellular Biology 16:3637-3650. Abstract
20. Friedberg, E.C., Bardwell, A.J., Bardwell, L., Feaver. W.J., Kornberg, R.D., Svejstrup, J.Q., Tomkinson, A.E. and Wang, Z. (1995) Nucleotide excision repair in the yeast Saccharomyces cerevisiae: its relationship to specialized mitotic recombination and RNA polymerase II basal transcription. Phil. Trans. R. Soc. London B 347:63-68. Also in Lindahl, T. and West, S.C. (Eds.), DNA Repair and Recombination. Chapman & Hall, London.
19. Bardwell, L., Cook, J.G., Inouye, C.J. and Thorner, J. (1994)
Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae.
Developmental Biology 166:363-379. Abstract
18. Bardwell, A.J., Bardwell, L.*, Tomkinson, A.E. and Friedberg, E.C. (1994) Specific cleavage of model recombination and repair intermediates by the yeast Rad1/Rad10 DNA endonuclease. Science 265:2082-2085. Abstract
17. Bardwell A.J., Bardwell L., Wang Z., Siede W., Reagan M.S., Tomkinson A.E., Friedberg A.S., Pittenger C., Feaver W.J., Svejstrup J., et al. (1994) Recent insights on DNA repair. The mechanism of damaged nucleotide excision in eukaryotes and its relationship to other cellular processes. Annals N.Y. Academy of Science 726:281-91.
16. Bardwell, A.J., Bardwell, L.*, Iyer, N., Svejstrup, J.Q., Feaver, W.J., Kornberg, R.D. and Friedberg, E.C. (1994) Yeast nucleotide excision repair proteins Rad2 and Rad4 interact with RNA polymerase II transcription factor b (TFIIH). Molecular and Cellular Biology 14:3569-3576. Abstract
15. Bardwell, L.*, Bardwell, A.J., Feaver, W.J., Svejstrup, J.Q., Kornberg, R.D. and Friedberg, E.C. (1994) Yeast RAD3 protein binds directly to both SSL2 and SSL1 proteins: implications for the structure and function of transcription/ repair factor b. Proc. Natl. Acad. Sci. USA 91:3926-3930. Abstract
14. Friedberg, E.C., Bardwell, A.J., Bardwell, L., Wang, Z. and Dianov, G. (1994) Transcription and nucleotide excision repair- reflections, considerations and recent biochemical insights. Mutation Research 307:5-14. Abstract
13. Feaver, W.J., Svejstrup, J.Q., Bardwell, L., Bardwell, A.J., Buratowski, S., Gulyas, K.D., Donahue, T.F., Friedberg, E.C. and Kornberg, R.D. (1993) Dual roles of a multi-protein complex from S. cerevisiae in transcription and DNA repair. Cell 75:1379-1387. Abstract
12. Bardwell, A.J., Bardwell, L.*, Johnson, D.K. and Friedberg, E.C. (1993) Yeast DNA recombination and repair proteins Rad1 and Rad10 constitute a complex in vivo mediated by localized hydrophobic domains. Molecular Microbiology 8:1177-1188. Abstract
11. Tomkinson, A.E., Bardwell, A.J., Bardwell, L., Tappe, N.J. and Friedberg, E.C. (1993) Yeast DNA repair and recombination proteins Rad1 and Rad10 constitute a single-stranded DNA endonuclease. Nature 362:860-862. Abstract
10. Naegeli, H., Bardwell, L. and Friedberg, E.C. (1993) Inhibition of Rad3 DNA helicase activity by DNA adducts and abasic sites: Implications for the role of a DNA helicase in damage-specific incision of DNA. Biochemistry 32:613-621. Abstract
9. Bardwell, L., Cooper, A.J. and Friedberg, E.C. (1992) Stable and specific association between the yeast recombination and DNA repair proteins RAD1 and RAD10 in vitro. Molecular and Cellular Biology 12:3041-3049. Abstract
8. Friedberg, E.C., Bardwell, L. and Naegeli, H. (1992) What can yeast tell us about cancer pathogenesis and cancer proneness? In Bohr, V.A., Wasserman, K., and Kraemer, K.A. (Eds.), Alfred Benzon Symposium No. 35: DNA Repair Mechanisms. Munksgaard, Denmark. pp. 80-89.
7. Naegeli, H., Bardwell, L.. and Friedberg, E.C. (1992) Substrate specificity of the Rad3 ATPase/DNA helicase of Saccharomyces cerevisiae and binding of Rad3 protein to nucleic acids. Journal of Biological Chemistry 267:7839-7844. Abstract
6. Naegeli, H., Bardwell, L. and Friedberg, E.C. (1991) The DNA helicase and adenosine triphosphatase activities of yeast Rad3 protein are inhibited by DNA damage: a potential mechanism for damage-specific recognition. Journal of Biological Chemistry 267:392-398. Abstract
5. Bardwell, L., Burtscher, H., Weiss, W.A., Nicolet, C.M. and Friedberg, E.C. (1990) Characterization of the RAD10 gene of Saccharomyces cerevisiae and purification of Rad10 protein. Biochemistry 29:3119-3126. Abstract
4. Bardwell, L. (1989) The mutagenic and carcinogenic effects of gene transfer. Mutagenesis 4:245-253. Abstract
3. Kaden, D.A., Bardwell, L., Newmark, P., Anisowicz, A., Skopek, T.R. and Sager, R. (1989) High frequency of large spontaneous deletions of DNA in tumor-derived CHEF cells. Proc. Natl. Acad. Sci. USA 86:2306-10. Abstract
2. Kaden, D., Gadi, I.K., Bardwell, L., Gelman, R. and Sager, R. (1989) Spontaneous mutation rates of tumorigenic and nontumorigenic Chinese hamster embryo fibroblast cell lines. Cancer Research 49:3374-79. Abstract
1. Anisowicz, A., Bardwell, L. and Sager, R. (1987) Constitutive overexpression of a growth-regulated gene in transformed Chinese hamster and human cells. Proc. Natl. Acad. Sci. USA 84:7188-92. Abstract
* = These are "co-first author" papers
Last modified 13 September 2006. Back to top