Bardwell Lab: Useful links

NCBI:

Protein-Protein Interactions:

Kinases/Phosphorylation

Pathway Modeling

Yeast

· SGD: Saccharomyces Genome Database

· Yeast GFP fusion localization resource

· Triples database (Snyder transposon insertion)

· Yeast Protein Complex Database (Cellzome) data from Gavin et. al. Nature 415, 411-417 (2002)

· Yeast Microarray Global Viewer

Genome Databases

· Human

Human Genome Resources from NCBI.
Mendelian Inheritance In Man online database.
Genecards, a database of human genes, their products and their involvement in disease.
Human Gene Mutation Database at Cardiff.

Mutations in CDK4 or p16/INK4/CDKN2 in familial melanoma.
p57KIP2/CDKN1C mutations in Beckwith-Wiedemann syndrome.
RB1 mutations in Retinoblastoma.
p53 mutations in Li-Fraumeni syndrome and various cancers.

Cancer-related Genes listed alphabetically and by chromosomal locus. Note that a small proportion of these have been shown to be mutated or rearranged in human cancers.
Cancer information from the National Cancer Institute.

· Mouse

The Transgenic/Targeted Mutation Database, Jackson Laboratory.
Mouse gene knock-outs listed alphabetically, not searchable.
Other transgenic databases.

· Fly (Drosophila)

Flybase

· Worm (C. elegans)

Wormbase

· Yeast (S. cerevisiae)

Saccharomyces Genome Database

Relations Between Biological Entities (genes, proteins, pathways)

BRITE database (Biomolecular Relations)

Misc Sequence Prediction Servers

CBS Prediction Servers Center for Biological Sequence Analysis

MicroArrays/Gene Expression